AGE: 46
OCCUPATION: Actor, director, producer, movie star
NUMBER OF TIME COVERS: 1
PREVIOUS APPEARANCES ON THE TIME 100: 2
PRO: Nominated for a fourth Oscar last year (Best Actor, Michael Clayton), Clooney's easy charm only grows: he'll surely work against it once again in a new Coen brothers movie. He cultivates two critical, seemingly incompatible characteristics: he's deeply, passionately involved in everything from Hollywood politics to Washington politics to world politics — yet he carries himself like he couldn't care less.
CON: After a year of catching malaria and running around war zones, he admits that all the celebrity intervention in the world won't save Darfur — and that, in some cases, it's possible for a star to make things worse. Also: that Leatherheads trailer looks...awful.